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Figure 2 | AIDS Research and Therapy

Figure 2

From: IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells

Figure 2

Effects of stimulation on memory cell markers. A CMV-positive whole blood sample from a healthy donor was incubated for six hours with pp65 peptide, in the presence of brefeldin A. Phenotypic analysis was performed both before and at various time points during stimulation. A: Gating on CMV tetramer-positive cells, the response to stimulation after six hours is demonstrated by the release of cytokine. By isolating the tetramer-positive IFNγ+ cells, it is evident that there are only nominal changes in the proportions of memory cell markers after six hour stimulation. B: Changes in each individual phenotype over time are shown. Results are expressed as absolute number of cells per milliliter of blood.

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