TY - JOUR AU - Siegert, Sandra AU - Thaler, Sonja AU - Wagner, Ralf AU - Schnierle, Barbara S. PY - 2005 DA - 2005/09/12 TI - Assessment of HIV-1 entry inhibitors by MLV/HIV-1 pseudotyped vectors JO - AIDS Research and Therapy SP - 7 VL - 2 IS - 1 AB - Murine leukemia virus (MLV) vector particles can be pseudotyped with a truncated variant of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) and selectively target gene transfer to human cells expressing both CD4 and an appropriate co-receptor. Vector transduction mimics the HIV-1 entry process and is therefore a safe tool to study HIV-1 entry. SN - 1742-6405 UR - https://doi.org/10.1186/1742-6405-2-7 DO - 10.1186/1742-6405-2-7 ID - Siegert2005 ER -