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Figure 2 | AIDS Research and Therapy

Figure 2

From: Monitoring processed, mature Human Immunodeficiency Virus type 1 particles immediately following treatment with a protease inhibitor-containing treatment regimen

Figure 2

Western blot analyses for the HIV-1 gag proteins in patient plasma prior to and following ARV treatment. Patient plasma was obtained at 0, 4, 8, 12, 24, 72 hours and 4 weeks following ARV treatment. Plasma was diluted with serum-free media and then centrifuged to pellet HIV-1 particles prior to the analyses (see Fig. 1). Panel A shows the Western blot results on plasma samples obtained from patient A who was treated with NVP+3TC+D4T+ABV and patient B who was treated with LPV+NVP. Panel B shows the ratios of unprocessed p55gag to processed CA p24 in patients treated with NVP+3TC+D4T+ABV (patient A) or NVP+LPV (patient B, C, and D). Each bar at each time point represents analyses from a separate Western blot. Panel C is a plot showing the changes in CD4 cell count (cells/mm3; open squares) and viral RNA load in plasma (copies/ml, filled diamonds) following treated with either treatment regimen.

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AIDS Research and Therapy

ISSN: 1742-6405

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