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Table 1 TDF dose reduction strategies

From: A consensus statement on the renal monitoring of Australian patients receiving tenofovir based antiviral therapy for HIV/HBV infection

Creatinine clearance

Dosing interval for TDF 300 mg

(or eGFR – CKD-EPI)

 

>50

Every 24 hrs

30-49

Every 48 hrs*

10-29

Every 72–96 hrs*

Haemodialysis

After dialysis every 7 days or after ~12 hrs of dialysis*

  1. *Consider whether TDF is the appropriate antiviral.