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Table 3 Plasma Lipid levels changes from switch to ≥48 weeks on second-line ART

From: Impact of second-line antiretroviral regimens on lipid profiles in an African setting: the DART trial sub-study

 

Initiation of second-line (mean; sd)

48 weeks later (mean; sd)

Changes (SE)

% Change

P-value

 

n = 65

n = 65

n = 65

  

TC

3.4 (1.0)

5.4 (1.2)

+2.0 (0.1)

59%

<0.001

LDL-C

1.8 (0.7)

2.8 (0.9)

+1.1 (0.1)

61%

<0.001

HDL-C

0.7 (0.2)

1.2 (0.4)

+0.5 (0.05)

71%

<0.001

TG

1.4 (1.0)

1.9 (1.3)

+0.4 (0.2)

29%

0.01

TC/HDLC-C

4.9 (1.4)

4.9 (2.1)

+0.0 (0.3)

0%

0.94