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Table 1 Selected peptides and corresponding avidities of TCR/HLA-A2/peptide interaction

From: Greater frequency of CD5-negative CD8+ T cells against human immunodeficiency virus type 1 than other viruses is consistent with adaptation to antigenic variation

Peptide

Protein and location

Sequence

Avidity

CMV

pp65 495-503

NLVPMVATV

1.0 nM

Flu

Matrix 55-63

GILGFVFTL

250 nM

EBV

BMLF1 280-288

GLCTLVAML

500 nM

IP-30

IP-30 -11 to -3

LLDVPTAAV

2.0 μM

Gag

p17 77-85

SLYNTVATL

50 nM

RT1

RT 33-41

ALVEICTEM

10 nM

RT2

RT 179-187

VIYQYMDDL

10 nM

PR

PR 76-84

LVGPTPVNI

0.1 nM