The percentage of HIV peptide-specific CD8+T cells expressing CD5 and comparison to other virus peptide and self-peptide-specific CD8+T cells. (a) Solid columns represent median values for each individual peptide (identified below the column) with error bars showing interquartile range and n within each column indicating the number of individuals with specific proliferation against each individual peptide. (b) Box and whisker plots showing median percentages of non-HIV viral peptide, HIV peptide and self peptide-specific CD8+ T cells expressing CD5 for healthy controls (grey boxes) and HIV-infected individuals (white boxes). Horizontal lines within the box represent the median, with boxes illustrating interquartile range and vertical error bars indicating overall range. Significant differences between medians are shown by p values above lines bracketing the relevant groups (Mann–Whitney test).