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Table 2 Characteristics of children on NNRTI-based and PI-based regimens (based on regimen at time of genotype)

From: Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort

  NNRTI (n = 73) PI (n = 16)
At ART initiation   
Age, years, median (IQR)** 7.6 (5.2-10) 1.5 (0.7-3.8)
CD4+ cell count, cells/μl, median (IQR)* 256 (108–477) 647 (112–817)
Viral load, log10 copies/ml, median (IQR) 3.9 (3.7-4.2) 4.7 (4.7-4.7)
At Genotyping   
Age at genotyping, years, median (IQR) 11.4 (8.9-13.4) 5.0 (2.7-7.5)
CD4+ cell count prior to genotyping, cells/μl, median (IQR)** 379 (167–668) 762 (603–1123)
Viral load prior to genotyping, log10 copies/ml, median (IQR) 4.3 (3.8-4.8) 4.3 (3.8-5.2)
Comparative measures   
Duration of ART, years, median (IQR) 3.4 (2.6-4.5) 2.7 (1.6-4.0)
Duration of ART failure, years, median (IQR) 1.8 (0.9-2.4) 1.6 (0.8- 2.3)
Time between last viral load and genotyping, months, median (IQR) 3.3 (1.6-7.1) 3.0 (1.1-4.85)
  1. Key: Difference in means at a 1% (**) or 5% (*) level of significance using the Student’s T-Test.