The development of simple anthropometric measures to diagnose antiretroviral therapy-associated lipodystrophy in resource limited settings

Table 5 Variables for prediction and classification used to identify lipoatrophy and lipohypertrophy cut-points

Lipoatrophy variable cut-point	N	Sensitivity	Specificity	Likelihood ratio positive test	Likelihood ratio negative test	Positive predictive value	Negative predictive value	% correctly classified
Tricep skinfold ≤14.5 mm	418	0.62	0.71	2.13	0.53	0.42	0.85	68.66*
Thigh skinfold ≤28.0 mm	417	0.67	0.65	1.93	0.51	0.39	0.85	65.70*
% Lower limb fat/height ≤ 24.7	418	0.19	0.85	1.28	0.95	0.30	0.76	68.42*
Lower limb fat (%) ≤ 39.1	418	0.19	0.84	1.20	0.96	0.29	0.75	67.70*
Lipohypertrophy variable cut-point
Waist/Hip Ratio ≥ 0.899	434	0.44	0.75	1.75	0.75	0.46	0.73	64.75**
Waist Circumference ≥ 88.5 cm	434	0.57	0.59	1.40	0.73	0.41	0.73	58.53**
Trunk fat/total limb fat (%) ≥0.8895	172	0.50	0.70	1.66	0.72	0.38	0.79	64.5**
Trunk fat/leg fat (%) ≥ 0.8816	172	0.72	0.61	1.84	0.46	0.40	0.86	64.0**

*percentage of those classified with and without lipoatrophy using the new cut-point compared to those defined by subject-report.
**percentage of those classified with and without lipohypertrophy using the new cut-point compared to those defined by subject-report.

ISSN: 1742-6405