The development of simple anthropometric measures to diagnose antiretroviral therapy-associated lipodystrophy in resource limited settings

Table 1 Characteristics of participants on ART

Variable	Lipoatrophy*		P-value**	Lipohypertrophy***		P-value**
Variable	With n = 121 Median [IQR]	Without n = 429 Median [IQR]	P-value**	With n = 157 Median [IQR]	Without n = 393 Median [IQR]	P-value**
Age	34 [30–42]	35 [30–41]	0.256	34 [29–41]	35 [30–41]	0.198
Current CD4 count	397 [249–539]	315 [218–481]	0.023	389 [248–548]	314 [220–481]	0.015
Time on ART (months)	25 [14–32]	17 [10–27]	0.001	20 [12–31]	17 [11–28]	0.080
Time on Stavudine (months)	15.5 [10–26]	13 [8–19]	0.004	13 [8–21]	13 [9–20]	0.961
	n [%]	n [%]		n [%]	n [%]
Sex
Males	12 [10.34]	104 [89.66]	0.001	15 [12.93]	101 [87.07]	<0.001
Females	109 [25.12]	325 [74.88]		142 [32.72]	292 [67.28]
Highest standard passed
No schooling	6 [18.8]	26 [81.3]	0.289	9 [28.13]	23 [71.88]	0.272
Primary school	14 [15.4]	77 [84.6]		20 [21.98]	71 [78.02]
Secondary school	96 [23.4]	315 [76.6]		121 [29.44]	290 [70.56]
Tertiary	5 [31.3]	11 [68.8]		7 [43.75]	9 [56.25]
ART Regimen
First-line	99 [22.30]	345 [77.70]	0.730	130 [29.28]	314 [70.72]	0.608
Second-line	22 [20.75]	84 [79.25]		27 [25.47]	79 [74.53]

*based on patient report, those with moderate or severe fat loss in 2 or more regions.
**Wilcoxon Rank-sum (Mann–Whitney) tests for continuous variables and chi-square tests for binary variables.
***based on patient report, those with moderate or severe fat gain in 2 or more regions.

ISSN: 1742-6405