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Table 3 Baseline characteristics of HCV/HIV co-infected patients (HCV treated versus untreated)

From: German cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients

Characteristics Group A: HCV/HIV co-infected patients, treated (n = 36) Group B: HCV/HIV co-infected patients, untreated (n = 52) p-values
Age, mean (min./max.) 47 (26/64) 45 (27/61) 0.040
Sex, male/female (%) 26/10 (72/28) 40/12 (77/23) 0.617
Genotype, n (%)    
 1 15 (42) 22 (42) 0.952
 2 2 (6) 1 (2) 0.356
 3 14 (39) 11 (21) 0.070
 4 1 (2) 1 (2) 0.791
 Unknown 4 (11) 17 (33) 0.020
Transmission of HCV, n (%)    
 IVDU 21 (58) 37 (71) 0.212
 Transfusion 4 (11) 3 (6) 0.363
 Needlestick injury 0 (0) 0 (0) n.a.
 Tatoo 0 (0) 0 (0) n.a.
 Sex 1 (3) 3 (6) 0.508
 Unknown 10 (28) 9 (17) 0.241
CDC Classification, n (%)    
 A1 – A3 13 (36) 10 (19) 0.005
 B1 – B3 9 (25) 7 (13) 0.168
 C1 – C3 9 (25) 22(42) 0.059
 Unknown 5 (13) 14 (26) 0.144
Liver biopsy, n (%) 7/36 (19) 5/52 (9) 0.186
 Fibrosis F3 – F4, n (%) 5/7 (71) 1/5 (20) 0.029
HCV RNA in IU/ml, mean (min./max.) 4800 000 (800/9 × 107) 4 713 000 (3/6 × 107) 0.965
CD4 Count absolute, mean 553,1 396,73 0.001
 CD4 Count > 200/μl, n (%) 25 (69) 21 (40) 0.007
 CD4 Count < 200/μl, n 2 (3,5) 16 (30) 0.004
 CD4 Count unknown, n (%) 7 (19) 15 (28) 0.317
CD4 Count relative, mean 27,9 22,2 0.001
CD4 Nadir in cells/μl, mean 208 194 0.689
CD4/CD8 Ratio, mean 0,67 0,49 0.001
HIV RNA in copy/ml, mean (minimum/maximum) 9 850 (3/16 × 104) 71 180 (3/12 × 105) 0.015
HIV Treatment, n (%) 29 (36) 0 (0) n.a.
 NRTI, n (%) 20/29 (68) n.a. n.a.
 NNRTI, n (%) 18/29 (62) n.a. n.a.
 PI, n (%) 12/29 (41) n.a. n.a.
 Intregrase Inh., n (%) 2/29 (6) n.a. n.a.
 Entry Inh., n (%) 0 (0) n.a. n.a.