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Table 5 Factors associated with early initiation of primary PCP prophylaxis from 1998-2009

From: Race/ethnicity and HAART initiation in a military HIV infected cohort

  Univariate models Multivariate model*
  Initiators (N = 156) N (%) or median (IQR) Delayers (N = 252) N (%) or median (IQR) OR (95% CI) p OR (95% CI) P
Demographics
Gender (% Male) 144 (92%) 227 (90%) 1.32 (0.64 - 2.71) 0.45 1.00 (0.33 - 3.03) >0.99
Age 36.9 (29.2 - 43.0) 37.4 (32.2 - 42.5) 0.99 (0.97 - 1.01) 0.36 0.98 (0.95 - 1.01) 0.27
Race/ethnicity
 Caucasian 61 (39%) 100 (40%) Referent   Referent  
 African American 72 (46%) 122 (48%) 0.97 (0.63 - 1.49) 0.88 1.21 (0.71 - 2.09) 0.48
 Hispanic/Latino/other 23 (15%) 30 (12%) 1.26 (0.67 - 2.36) 0.48 1.35 (0.61 - 3.00) 0.46
Marital status (% married) 63 (41%) 71 (31%) 1.50 (0.98 - 2.30) 0.06 1.52 (0.89 - 2.59) 0.12
Military characteristics
Rank
 Officer/warrant 19 (12%) 24 (10%) 1.33 (0.70 - 2.54) 0.38 1.76 (0.74 - 4.15) 0.20
 Enlisted 121 (78%) 199 (79%) Referent   Referent  
 N/A 16 (10%) 24 (10%) 1.12 (0.57 - 2.20) 0.73 1.72 (0.54 - 5.47) 0.36
Duty status
 Active 82 (53%) 109 (43%) Referent   Referent  
 Retired 63 (40%) 118 (47%) 0.71 (0.47 - 1.08) 0.11 1.16 (0.59 - 2.25) 0.67
 Dependent 11 (7%) 25 (10%) 0.58 (0.27 - 1.26) 0.17 0.36 (0.09 - 1.53) 0.17
HIV characteristics
Duration of HIV infection (years) 2.5 (0.1 - 8.8) 6.6 (1.8 - 10.9) 0.93 (0.89 - 0.97) <0.001 0.99 (0.93 - 1.05) 0.70
Log10 HIV RNA 4.8 (4.3 - 5.2) 4.5 (3.6 - 5.0) 1.49 (1.21 - 1.83) <0.001 1.25 (0.98 - 1.60) 0.07
CD4 count* 130.0 (68.5 - 167.0) 169.0 (131.5 - 187.0) 0.59 (0.49 – 0.72) <0.001 0.55 (0.42 – 0.70) <0.001
Prior ART use
 None 92 (59%) 81 (32%) Referent   Referent  
 ART 14 (9%) 24 (10%) 0.51 (0.25 - 1.06) 0.07 0.81 (0.30 - 2.15) 0.67
 HAART 50 (32%) 147 (58%) 0.30 (0.19 - 0.46) <0.001 0.48 (0.25 - 0.91) 0.03
Prior AIDS 24 (15%) 36 (14%) 1.09 (0.62 - 1.91) 0.76 1.00 (0.45 - 2.19) >0.99
History of mental health diagnosis
 Depression 19 (12%) 46 (18%) 0.63 (0.35 - 1.13) 0.12 0.82 (0.41 - 1.65) 0.58
 Other mental health diagnosis 13 (8%) 16 (6%) 1.24 (0.58 - 2.68) 0.58 1.52 (0.61 - 3.79) 0.36
 None 124 (79%) 190 (75%) Referent   Referent  
  1. *Univariate and Multivariate models are per 50 cells/mm3.