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Table 1 Study group classifications according to changes in the DHHS guidelines for initiation of antiretroviral therapy in chronically-infected HIV patients1

From: Race/ethnicity and HAART initiation in a military HIV infected cohort

Group 1998-2000 2001 2002-2004 2005-2007 2008-2009
A •  AIDS-defining condition •  AIDS-defining condition •  AIDS-defining condition •  AIDS-defining condition •  AIDS-defining condition
•  Severe symptoms •  Severe symptoms •  Severe symptoms •  Severe symptoms •  Severe symptoms
•  CD4+ <200 •  CD4+ <200 •  CD4+ <200 •  CD4+ <200
B •  CD4+ <500 •  CD4+ >200 but ≤350 •  CD4+ >200 but ≤350 •  CD4+ >200 but ≤350 •  CD4+ >200 but ≤350
•  VL >10,000 (bDNA) or >20,000 (RT-PCR)
C •  Elective decision •  VL >30,000 (bDNA) or >55,000 (RT-PCR) •  VL >55,000 (bDNA or RT-PCR) •  VL >100,000 (RT-PCR) •  CD4+ >350
•  CD4+ >350 •  CD4+ >350 •  CD4+ >350 •  Other elective decision
•  Other elective decision •  Other elective decision •  Other elective decision  
  1. 1Guideline statements of “some would treat” were interpreted as indicating the elective nature of this decision. Therefore viral load was not included as a Group B criterion after 2000.