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Figure 3 | AIDS Research and Therapy

Figure 3

From: The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity

Figure 3

Aβ(1–42) peptide boosted infectivity of Molt-4 T cells. (A) Equal amounts of the R4 tropic HIV-1 NL4-3 lab strain expressing a NEF-GFP fusion protein were pre-incubated for 5 min at RT with PBS only, Aβ(1–40) or Aβ(1–42) fibrils [10 μg/ml]. Subsequently, Molt-4 T cells were infected with the pre-treated viruses and the percentage of HIV-1 infected (GFP positive) cells was assayed by FACS analysis 48 h post infection. (B) The percentage of HIV-1 infected (GFP positive) cells.

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