From: Coregulation of HIV-1 dependency factors in individuals heterozygous to the CCR5-delta32 deletion
N= | Study population | Benefit tested | Significance | Reference |
---|---|---|---|---|
1427 | HIV + vs. sero-negative control group | Transmission | P = 0.012 | [8] |
30 | ESN | Transmission | P = 0.04 | [9] |
54 | ESN | Transmission | P = 0.05* | [10] |
2605 | Woman | Transmission | OR: 0.63 (95% CI 0.44-0.90) | [11] |
2996 | High risk groups | Transmission | Risk = 0.30 (95% CI: 0.08-0.97) | [12] |
1252 | MSM | Transmission | NS | [13] |
1200 | HIV + vs control | Transmission, progression to AIDS | Both significant | [14] |
108 | IDU | Progression to AIDS | NS | [15] |
127 | Children | Progression to AIDS | Significant (p = 0.008) Effect is abrogated in case of a SDF1-3′A genotype | [16] |
1955 | Hemophilia patients | Progression to AIDS | Significant | [17] |
512 | Mother-child | Transmission, progression to AIDS | NS, significant | [18] |