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Table 3 Clinical characteristics of HIV patients with or without chronic non HBV/HCV hepatitis at time of ALT elevation**

From: Risk factors of chronic hepatitis in antiretroviral-treated HIV infection, without hepatitis B or C viral infection

Clinical parameters

Case

Control

p value

 

(n = 124)

(n = 124)

 

BMI ≥ 23 kg/m 2 (n,%)

55(44.4)

26(20.9)

0.001*

Elevated blood pressure/ hypertension (n, %)

24(19.3)

18(14.5)

0.32

Metabolic syndrome (n, %)

3(4.3)

3(3.0)

0.66

Clinically-diagnosed lipodystrophy

14(11.3)

10(8.1)

0.32

Laboratory measurement (n, %)

   

o CD4+ cell count ≤ 200 cells/mm3

15(12.1)

10(8.1)

0.30

o HIV-1 RNA level ≥ 400 copies/ml

11(8.8)

16(9.6)

0.21

o Impaired fasting plasma glucose ≥ 100 mg/dL

15(14.1)

10(9.6)

0.21

o Total cholesterol ≥ 200 mg/dL

56(50.4)

48(42.8)

0.49

o Triglycerides ≥ 150 mg/dL

40(36.0)

31(27.7)

0.29

o HDL cholesterol ≤ 40 mg/dL (male) or ≤ 50 mg/dL (female)

36(34.3)

22(21.6)

0.09

o LDL cholesterol ≥ 130 mg/dL

36(34.3)

25(24.5)

0.32

  1. Abbreviation: HIV Human immunodeficiency virus, HBV Hepatitis B virus, HCV Hepatitis C virus, BMI Body mass index, HDL High density lipoprotein and LDL Low density lipoprotein.
  2. *Significant value with p value less than 0.05.
  3. **Chronic hepatitis was defined as those with elevated ALT ≥ 40 IU/L at 2 consecutive visits 6 months apart.